THALASSEMIAS
THALASSEMIAS are the group of hereditary disorders of hemolysis characterized by an imbalance in the synthesis of Globin chains of hemoglobin. Hemoglobin contains 2α and 2β globin chains. The synthesis of individual chains is coordinated in such a way that both chains combine. Defects of Thalassemia: Deletion or substitution of genes. mRNA gets unstable. Defective …