Formation of Cholesterol & methods of reduction
Acetyl-CoA is the source of all carbon atoms in Cholesterol. Cholesterol formation from Lanosterol takes place in the ER membranes. Methyl groups are removed from it to form 14-Desmethyl Lanosterol and then to form Zymosterol. Then double bonds are removed sequentially to form Cholestadienol then Desmosterol [24-dehydro Cholesterol] and the double bond of the side …